Living With Mesothelioma -My Diary- Channel 4 are having a Stand up to Cancer. Speech for Holland is accepted.

Yesterday was very dull all day so making us feel lazy and cake eating day.We did manage to go out and walk around the local football field. Making Louis run around to really tire him out.

Today is so sunny so we will get out and walk the dog.

I have been working away on the computer after clearing out cupboards and drawers. Christmas is rushing onto us and I must get in control.

I was so pleased to get an email from Holland to say Mickey loved my video speech. I can relax now. he loves the fact I have come over as just a housewife. The box of dog chews behind me on a shelf gave the clue .

Caught up in the slowness of Clinical Trials and their results. I know how great Im feeling and dealing with Mesothelioma after 5.6 years but I musnt really shout it to the world as we have to wait for the results to be published

MK-3475. The drug is an antibody that targets a protein expressed by immune cells called PD-1. In the body, PD-1 acts as an immune checkpoint, turning down the immune system’s T cells that otherwise would attack cancer cells as invaders. MK-3475 takes the brakes off the immune system and allows T cells to identify and attack cancer cells.

The U.S. Food and Drug Administration (FDA) granted breakthrough therapy designation to MK-3475 for unresectable or metastatic melanoma in May 2013 under its Accelerated Approval program.

In UCLA clinical trials, doctors are seeing unprecedented treatment success with MK-3475 in two types of cancer that have historically had very low survival rates. The first is metastatic melanoma, a malignant skin cancer that spreads (metastasizes) aggressively beyond the initial tumor to invade other vital organs, such as brain, lungs or liver. The other is lung cancer, the cause of the highest number of cancer deaths in the U.S. year after year.

I cant wait to see these results so that Phase 1 can begin for the Mesowarriors who have to wait until next year.

Im not getting any side effects but some people are.

I found a forum for the drug

So you can see the drug is being tolorated well.

I watched a wonderful program last night

Channel 4 and Cancer Research UK’s Stand Up To Cancer – a joint national fundraising campaign including a  fortnight of inspirational programming and culminating on Friday 17th October in one raucous night of fundraising hosted by Davina McCall, Alan Carr and Dr Christian Jessen.

Our incredible trail launched last Friday, and has so far achieved over one million views on Youtube, as well as hitting a TV audience of over 10 million last weekend. This unmissable moment is just a taster of what’s to come, as we prepare to show cancer – it’s Payback Time.

Please see that Trials are the way to go for treatment as things are changing all the time and there are some wonderful People trying hard to find a cure for us. We are terminal so we have nothing to lose. We can infact help the future so changing our Negative into a positive.

Treatments are developed and tested in laboratories. For ethical and safety reasons, experimental treatments must be tested in the laboratory before they can be tried in patients. If a treatment described here is said to be at the laboratory stage of research, it is not ready for patients and is not available either within or outside the NHS. Cancer Research UK supports a lot of UK laboratory research into cancer.



Rays Blog



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